diff --git a/requirements.txt b/requirements.txt
index 4bc58e08c..cd4a89ad9 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -12,16 +12,16 @@ Flask-Migrate==2.7.0
 git+https://github.com/mitsuhiko/flask-sqlalchemy.git@500e732dd1b975a56ab06a46bd1a20a21e682262#egg=Flask-SQLAlchemy==2.3.2.dev20190108
 Flask==1.1.2
 click-datetime==0.2
-eventlet==0.30.1
-gunicorn==20.0.4
+eventlet==0.30.2
+gunicorn==20.1.0
 iso8601==0.1.14
 itsdangerous==1.1.0
 jsonschema==3.2.0
-marshmallow-sqlalchemy==0.23.1 # pyup: <0.24.1 # marshmallow v3 throws errors
+marshmallow-sqlalchemy==0.23.1 # pyup: <0.24.0 # marshmallow v3 throws errors
 marshmallow==2.21.0 # pyup: <3 # v3 throws errors
 psycopg2-binary==2.8.6
 PyJWT==2.0.1
-SQLAlchemy==1.3.23
+SQLAlchemy==1.4.5
 strict-rfc3339==0.7
 rfc3987==1.3.8
 cachetools==4.2.1
@@ -29,7 +29,7 @@ beautifulsoup4==4.9.3
 lxml==4.6.3
 # higher version causes build to fail on PaaS due to lack of Rust
 # see https://github.com/pyca/cryptography/issues/5810
-cryptography<3.4
+cryptography==3.4.7
 
 notifications-python-client==6.0.2
 
@@ -39,7 +39,7 @@ awscli-cwlogs==1.4.6
 git+https://github.com/alphagov/notifications-utils.git@44.1.0#egg=notifications-utils==44.1.0
 
 # gds-metrics requires prometheseus 0.2.0, override that requirement as 0.7.1 brings significant performance gains
-prometheus-client==0.9.0
+prometheus-client==0.10.0
 gds-metrics==0.2.4
 
 ## The following requirements were added by pip freeze:
@@ -47,14 +47,14 @@ alembic==1.5.8
 amqp==1.4.9
 anyjson==0.3.3
 attrs==20.3.0
-awscli==1.19.39
+awscli==1.19.47
 bcrypt==3.2.0
 billiard==3.3.0.23
 bleach==3.3.0
 blinker==1.4
 boto==2.49.0
-boto3==1.17.39
-botocore==1.20.39
+boto3==1.17.47
+botocore==1.20.47
 certifi==2020.12.5
 chardet==4.0.0
 click==7.1.2
@@ -66,6 +66,7 @@ geojson==2.5.0
 govuk-bank-holidays==0.8
 greenlet==1.0.0
 idna==2.10
+importlib-metadata==3.10.0
 Jinja2==2.11.3
 jmespath==0.10.0
 kombu==3.0.37
@@ -74,7 +75,7 @@ MarkupSafe==1.1.1
 mistune==0.8.4
 orderedset==2.0.3
 packaging==20.9
-phonenumbers==8.12.20
+phonenumbers==8.12.21
 pyasn1==0.4.8
 pycparser==2.20
 pyparsing==2.4.7
@@ -87,13 +88,15 @@ pytz==2021.1
 PyYAML==5.4.1
 redis==3.5.3
 requests==2.25.1
-rsa==4.5
+rsa==4.7.2
 s3transfer==0.3.6
 Shapely==1.7.1
 six==1.15.0
 smartypants==2.0.1
 soupsieve==2.2.1
 statsd==3.3.0
+typing-extensions==3.7.4.3
 urllib3==1.26.4
 webencodings==0.5.1
 Werkzeug==1.0.1
+zipp==3.4.1